Browsing by Author "Xu, Lulu"

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Knockdown of versican 1 blocks cigarette-induced loss of insoluble elastin in human lung fibroblasts

Xu, Lulu; Lu, Yuntao; Zhang, Jing; Wu, Lian; Merrilees, Mervyn J.; Qu, J. (Elsevier, 2015-05-11)

COPD lung is characterized by loss of alveolar elastic fibers and an increase in the chondroitin sulfate (CS) matrix proteoglycan versican 1 (V1). V1 is a known inhibitor of elastic fiber deposition and this study investigates ...