Browsing Health Sciences Journal Articles by Author "48061"
Now showing items 1-20 of 30
-
Adjusting protocols in clinical research: finding the point of cultural/clinical fusion
Pitama, S.G.; Cameron, Vicky A.; Huria, T.; Tikao-Mason, K.N.; Faatoese, Allamanda F.; Whalley, Gillian (2011)The Hauora Manawa/Heart Health: Community Heart Study is a research project currently being undertaken at the University of Otago, Christchurch. The purpose of this study is to identify the prevalence of cardiovascular ... -
Association between endothelin type A receptor haplotypes and mortality in coronary heart disease
Whalley, Gillian (2012)Coronary heart disease (CHD) encompasses a range of conditions including unstable angina, acute myocardial infarction (MI) and sudden ischemic death, characterized by the common pathophysiologic process of atherosclerotic ... -
The cardiac sonography workforce in New Zealand
Buckley, Belinda A.; White, Steve; Poppe, K.K.; Whalley, Gillian (Minnis Communications, 2013)Abstract Introduction: The aim of this paper is to investigate the cardiac sonography workforce characteristics and registration requirements in New Zealand (NZ), with a comparison to similar workforces internationally. ... -
Chronic measurement of left ventricular pressure in freely moving rats
Stehlin, Ellyce; Malpas, Simon C.; Budgett, David M.; Barrett, Carolyn J.; McCormick, Daniel; Whalley, Gillian; Fu, Fumin; Beil, Michael; Rigel, Dean F.; Guild, Sarah-Jane (American Physiological Society, 2013-10-08)Measurements of left ventricular pressure (LVP) in conscious freely moving animals are uncommon yet could offer considerable opportunity for understanding cardiovascular disease progression and treatment. The aim of this ... -
Community screening for cardiovascular risk factors and levels of treatment in a rural Māori cohort
Whalley, Gillian; Faatoese, A.F.; Pitama, S.G.; Doughty, R.N.; Richards, A.M.; Sheerin, I.G.; Cameron, V.A.; Troughton, R.W.; Gillies, T.W.; Huria, T.; Tikao-Mason, K.N.; Wells, J.E. (2011)Objectives: To document levels of cardiovascular disease (CVD), diagnosed and undiagnosed risk factors and clinical management of CVD risk in rural Māori. Methods: Participants (aged 20-64 years), of Māori descent and ... -
Differing prognostic value of pulse pressure in patients with heart failure with reduced or preserved ejection fraction: results from the MAGGIC individual patient meta-analysis
Jackson, Colette E.; Castagno, Davide; Maggioni, A.P.; Køber, Lars; Squire, I.B.; Swedberg, Karl; Andersson, Bert; Richards, A.M.; Bayes-Genis, Antoni; Tribouilloy, Christophe; Dobson, Joanna; Ariti, Cono A.; Poppe, K.K.; Earle, Nikki; Whalley, Gillian; Pocock, Stuart J.; Doughty, Robert N.; McMurray, John J.V. (European Society of Cardiology, 2015-01-23)AIMS: Low pulse pressure is a marker of adverse outcome in patients with heart failure (HF) and reduced ejection fraction (HFREF) but the prognostic value of pulse pressure in patients with HF and preserved ejection ... -
Gender and survival in patients with heart failure: interactions with diabetes and aetiology. Results from the MAGGIC individual patient meta-analysis
Martínez-Sellés, Manuel; Whalley, Gillian; Doughty, Robert N.; Poppe, K.K.; Earle, Nikki; Tribouilloy, Christophe; McMurray, John J.V.; Swedberg, Karl; Køber, Lars; Berry, Colin; Squire, I.B. (2012)While the populations of patients with heart failure (HF) studied in clinical trials are dominated by men, in routine clinical practice half or more of all patients with HF are women.1,2 Whether prognosis differs for men ... -
Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin b12 levels in post-acute coronary syndromes patients
Whalley, Gillian; Palmer, Barry R.; Slow, Sandy; Ellis, Katrina L.; Pilbrow, Anna P.; Skelton, Lorraine; Frampton, Chris M.; Palmer, Suetonia C.; Troughton, R.W.; Yandle, Tim G.; Doughty, Robert N.; Lever, Michael; George, Peter M.; Chambers, Stephen T.; Ellis, Chris J.; Richards, A.M.; Cameron, Vicky A. (Public Library of Science, 2014-03-11)Background and Aims: The methylene-tetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L) gene is involved in mitochondrial tetrahydrofolate metabolism. Polymorphisms in MTHFD1L, including rs6922269, have been ... -
Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients
Palmer, Barry R.; Slow, Sandy; Ellis, Katrina L.; Pilbrow, Anna P.; Skelton, Lorraine; Frampton, Chris M.; Palmer, Suetonia C.; Troughton, R.W.; Yandle, Tim G.; Doughty, Robert N.; Whalley, Gillian; Lever, Michael; George, Peter M.; Chambers, Stephen T.; Ellis, Chris J.; Richards, A.M.; Cameron, Vicky A. (Plos One, 2014-03-11)Background and Aims: The methylene-tetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (MTHFD1L) gene is involved in mitochondrial tetrahydrofolate metabolism. Polymorphisms in MTHFD1L, including rs6922269, have been ... -
Genetic variation in the renin–angiotensin–aldosterone system is associated with cardiovascular risk factors and early mortality in established coronary heart disease
Whalley, Gillian; Ellis, Katrina L.; Palmer, Barry R.; Frampton, Chris M.; Troughton, R.W.; Doughty, Robert N.; Ellis, Chris J.; Pilbrow, Anna P.; Skelton, Lorraine; Yandle, Tim G.; Richards, A.M.; Cameron, Vicky A. (2012)This study examined renin–angiotensin–aldosterone (RAAS) system gene variants for associations with cardiovascular risk factors and outcomes in coronary heart disease. Coronary disease patients (n¼1186) were genotyped for ... -
Genomic Risk Variants at 1p13.3, 1q41, and 3q22.3 Are Associated With Subsequent Cardiovascular Outcomes in Healthy Controls and in Established Coronary Artery Genomic Risk Variants at 1p13.3, 1q41, and 3q22.3 Are Associated With Subsequent Cardiovascular Outcomes in Healthy Controls and in Established Coronary Artery Disease
Whalley, Gillian; Ellis, Katrina L.; Frampton, Chris M.; Pilbrow, Anna P.; Troughton, R.W.; Doughty, Robert N.; Ellis, Chris J.; Skelton, Lorraine; Thomson, Judith; Yandle, Tim G.; Richards, A.M.; Cameron, Vicky A. (2011)Coronary artery disease (CAD) has multifactorial origins, and although some families are particularly affected, no precise mode of inheritance has been identified. It is likely that this reflects the contribution of numerous ... -
Heart failure in younger patients: the Meta-analysis Global Group in Chronic Heart Failure (MAGGIC)
Wong, Chih M.; Hawkins, Nathaniel M.; Petrie, Mark C.; Jhund, Pardeep S.; Gardner, Roy S.; Ariti, Cono A.; Poppe, K.K.; Earle, Nikki; Whalley, Gillian; Squire, I.B.; Doughty, Robert N.; McMurray, John J.V. (Oxford University Press on behalf of European Society of Cardiology, 2014-06-17)Aim Our understanding of heart failure in younger patients is limited. The Meta-analysis Global Group inChronic Heart Failure (MAGGIC) database, which consisted of 24 prospective observational studies and 7 randomized ... -
Heart failure with preserved ejection fraction
Whalley, Gillian; Rigolli, Marzia (The Institute of Geriatric Cardiology (IGC), Chinese PLA General Hospital and published by Science Press., 2013-12-27)Progressive aging of the population and prolongation of life expectancy have led to the rising prevalence of heart failure (HF). Despite the improvements in medical therapy, the mortality rate of this condition has remained ... -
Higher prevalence of left ventricular hypertrophy in two Māori cohorts: findings from the Hauora Manawa/Community Heart Study
Whalley, Gillian; Pitama, S.G.; Troughton, R.W.; Doughty, R.N.; Gamble, G.D.; Gillies, T.W.; Wells, J.E.; Faatoese, A.F.; Huria, T.; Richards, A.M.; Cameron, V.A. (Public Health Association of Australia, 2015-08)Objectives: Cardiovascular disease (CVD) is the leading cause of mortality in New Zealand with a disproportionate burden of disease in the Māori population. The Hauora Manawa Project investigated the prevalence of ... -
Hyperuricaemia and gout in New Zealand rural and urban Māori and non-Māori communities
Stamp, L. K.; Wells, J.E.; Pitama, S.G.; Faatoese, Allamanda F.; Doughty, Robert N.; Whalley, Gillian; Richards, A.M.; Cameron, Vicky A. (Wiley-Blackwell Publishing Asia, 2013-06)Background: There are few current data on the prevalence of hyperuricaemia and gout in New Zealand, particularly among the indigenous Māori population. Aims: To determine the prevalence of gout and hyperuricaemia in rural ... -
The Impact of Beta-blockade on Right Ventricular Function in Mitral Regurgitation
Hongning, Yin; Stewart, Ralph A.; Whalley, Gillian (Elsevier Inc, 2014-04)Background Although mitral regurgitation (MR) results in left ventricular (LV) volume overload, right ventricular (RV) function may also be impaired. We investigated the influence of short-term beta-blockade on RV function ... -
Known and missing left v entricular ejection fraction and survival in patients with heart failure : a MAGGIC meta-analysis report
Poppe, K.K.; Squire, I.B.; Whalley, Gillian (2013-06-26)Aims Treatment of patients with heart failure (HF) relies on measurement of LVEF. However, the extent to which EF isrecorded varies markedly. We sought to characterize the patient group that is missing a measure of EF, and ... -
Long-term outcomes in patients with restrictive filling following ST-segment elevation myocardial infarction
Hee, L.; Brennan, X.; Chen, J.; Allman, C.; Whalley, Gillian; French, J. K.; Juergens, C. P.; Thomas, L. (Wiley-Blackwell Publishing Asia, 2014-03-13)This study evaluated the effect of restrictive filling pattern (RFP) on 5-year outcomes in patients following ST-segment elevation myocardial infarction (STEMI). A hundred STEMI patients treated either by rescue or primary ... -
A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study
Whalley, Gillian (Oxford University Press on behalf of the European Society of Cardiology, 2014-11-18)Aim To develop age-, sex-, and ethnic-appropriate normative reference ranges for standard echocardiographic measurements of the left heart by combining echocardiographic measurements obtained from adult volunteers without ... -
Predicting survival in heart failure : a risk score based on 39 372 patients from 30 studies
Pocock, Stuart J.; Ariti, Cono A.; McMurray, John J.V.; Maggioni, A.P.; Køber, Lars; Squire, I.B.; Swedberg, Karl; Dobson, Joanna; Poppe, K.K.; Whalley, Gillian; Doughty, Robert N. (Oxford University Press, 2012-10-24)Aims: Using a large international database from multiple cohort studies, the aim is to create a generalizable easily used risk score for mortality in patients with heart failure (HF). Methods and results: Using a large ...