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dc.contributor.authorWhalley, Gillian
dc.contributor.authorRigolli, Marzia
dc.date.accessioned2015-10-13T01:51:13Z
dc.date.available2015-10-13T01:51:13Z
dc.date.issued2013-12-27
dc.identifier.issn1671-5411
dc.identifier.urihttps://hdl.handle.net/10652/3073
dc.description.abstractProgressive aging of the population and prolongation of life expectancy have led to the rising prevalence of heart failure (HF). Despite the improvements in medical therapy, the mortality rate of this condition has remained unacceptably high, becoming the primary cause of death in the elderly population. Almost half of patients with signs and symptoms of HF are found to have a nearly normal ejection fraction, which delineates a distinct clinical syndrome, known as HF with preserved ejection fraction (HF-PEF). While early research focused on the importance of diastolic dysfunction, more recent studies reported the pathophysiological complexity of the disease with multiple cardiovascular abnormalities contributing to its development and progression. HF-PEF is a challenging major health problem with yet no solution as there is no evidence-based treatment which improves clinical outcomes. This review summarizes the state of current knowledge on diagnosis, prognosis and treatment of HF-PEF, with particular insights on the pathological characteristics in the elderly population.en_NZ
dc.language.isoenen_NZ
dc.publisherThe Institute of Geriatric Cardiology (IGC), Chinese PLA General Hospital and published by Science Press.en_NZ
dc.rightsAll the contents published by this Open-Access journal could be distributed under the terms of the Creative Commons Attribution Noncommercial Share Alike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.en_NZ
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 New Zealand*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/nz/*
dc.subjectdiastoleen_NZ
dc.subjectechocardiographyen_NZ
dc.subjectmortalityen_NZ
dc.subjectpreserved ejection fractionen_NZ
dc.subjectheart failureen_NZ
dc.titleHeart failure with preserved ejection fractionen_NZ
dc.typeJournal Articleen_NZ
dc.rights.holderThe athorsen_NZ
dc.identifier.doidoi: 10.3969/j.issn.1671-5411.2013.04.011en_NZ
dc.subject.marsden110201 Cardiology (incl. Cardiovascular Diseases)en_NZ
dc.subject.marsden110308 Geriatrics and Gerontologyen_NZ
dc.identifier.bibliographicCitationRigolli, M. & Whalley, G.A. (2013).Heart failure with preserved ejection fraction. Journal of Geriatric Cardiology (2013) 10: 369−376. doi: 10.3969/j.issn.1671-5411.2013.04.011en_NZ
unitec.institutionUnitec Institute of Technologyen_NZ
unitec.institutionWaitakere Hospital, Aucklanden_NZ
unitec.institutionUniversity of Verona, Verona, Italyen_NZ
unitec.publication.spage369en_NZ
unitec.publication.lpage376en_NZ
unitec.publication.volume10en_NZ
unitec.publication.titleJournal of Geriatric Cardiologyen_NZ
unitec.peerreviewedyesen_NZ
dc.contributor.affiliationUnitec Institute of Technologyen_NZ
dc.contributor.affiliationWaitematā District Health Board (WDHB)en_NZ
dc.contributor.affiliationUniversity of Veronaen_NZ
unitec.identifier.roms55953en_NZ
unitec.institution.studyareaHealth Sciences


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