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dc.contributor.authorFluen, T.
dc.contributor.authorHardcastle, M.
dc.contributor.authorSmith, H. L.
dc.contributor.authorGear, Robyn
dc.date.accessioned2019-10-22T19:06:01Z
dc.date.available2019-10-22T19:06:01Z
dc.date.issued2019-09-23
dc.identifier.issn2399-2050
dc.identifier.urihttps://hdl.handle.net/10652/4758
dc.description.abstractAIMS To retrospectively determine the relative frequency of feline hepatobiliary diseases from biopsy specimens submitted to a single laboratory across a 10-year period and to establish whether age, sex or breed associations exist. METHODS Histopathological data from 154 liver biopsies of New Zealand cats sampled between 2008 and 2018 were analysed. The samples were allocated to primary, secondary and tertiary disease categories using criteria established by the World Small Animal Veterinary Association. Breed associations were derived using ORs and 95% CIs. Gender and age associations were also evaluated. RESULTS The most frequently diagnosed hepatobiliary diseases were lymphocytic cholangitis (20 per cent), hepatitis (16.9 per cent), reversible hepatocellular injury (16.4 per cent), neutrophilic cholangitis (9.7 per cent), haematopoietic neoplasia (9.7 per cent), hepatocellular neoplasia (5.6 per cent) and cholangiocellular neoplasia (4.1 per cent). Burmese cats were found to be at significantly increased risk of both biliary and parenchymal diseases and Birman cats to be at significantly increased risk of parenchymal disease. Domestic longhair cats were at significantly increased risk of hepatobiliary neoplasia. Birman cats were at significantly increased risk of hepatitis while domestic shorthair cats were at significantly decreased risk of neutrophilic cholangitis, reversible hepatocellular injury and hepatitis. CONCLUSIONS This study is the first retrospective examination of the relative frequency of hepatobiliary disease in biopsy specimens from New Zealand cats. Some breeds were associated with specific histopathologyen_NZ
dc.language.isoenen_NZ
dc.publisherBritish Veterinary Association (BVA)en_NZ
dc.relation.urihttps://vetrecordopen.bmj.com/content/6/1/e000367en_NZ
dc.rightsThis is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, an indication of whether changes were made, and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/.en_NZ
dc.subjectNew Zealanden_NZ
dc.subjectcats (Felis catus)en_NZ
dc.subjecthepatobiliary diseasesen_NZ
dc.subjectliver diseasesen_NZ
dc.subjecthepatic lipidosisen_NZ
dc.subjectdiagnosisen_NZ
dc.subjectincidenceen_NZ
dc.subjecthistopathologyen_NZ
dc.titleRetrospective study of the relative frequency of feline hepatobiliary disease in New Zealand based on 10years of hepatic biopsy samples.en_NZ
dc.typeJournal Articleen_NZ
dc.date.updated2019-10-15T13:30:28Z
dc.rights.holder© British Veterinary Association 2019.en_NZ
dc.identifier.doidoi:10.1136/vetreco-2019-000367en_NZ
dc.subject.marsden070709 Veterinary Pathologyen_NZ
dc.identifier.bibliographicCitationFluen, T., Hardcastle, M., Smith, H. L., & Gear, R .N. A. (2019). Retrospective study of the relative frequency of feline hepatobiliary disease in New Zealand based on 10 years of hepatic biopsy samples. Veterinary Record Open, 6:e000367, 1-8. doi:doi:10.1136/vetreco-2019-000367en_NZ
unitec.publication.spage1en_NZ
unitec.publication.lpage8en_NZ
unitec.publication.volume6:e000367en_NZ
unitec.publication.titleVeterinary Record Openen_NZ
unitec.peerreviewedyesen_NZ
dc.contributor.affiliationUnitec Institute of Technologyen_NZ
dc.contributor.affiliationVeterinary Internal Medicine Specialist (Auckland, N.Z.)en_NZ
dc.contributor.affiliationGribbles Veterinary Pathology New Zealand (Auckland, N.Z.)en_NZ
dc.contributor.affiliationMassey Universityen_NZ
unitec.identifier.roms64531en_NZ
unitec.publication.placeLondon, United Kingdomen_NZ
unitec.institution.studyareaNatural Sciences


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